The deceased man has been identified as 23-year-old Dwight Robinson.
Allegations are that Robinson was found by the landlord lying in a pool of blood in his room at about 3 am on Tuesday morning.
His room was ransacked and bloodied as it appeared there was a struggle between him and his attackers.
Based on preliminary investigations by the police, Robinson's attackers gained entry to his room through a window.
He was stabbed multiple times and was pronounced dead at hospital.
Robinson was a popular barber, who worked in Ocho Rios.